MULTICHANNEL DATA ACQUISITION,
State-of-the-art recording system: captures multi-channel data sets from Awake,
behaving or anesthetized rats, primates, or tissue culture plates. Data is obtained from awake, behaving rats or primates, anesthetized rats or primates, or from human surgical subjects using multiple arrays of micro wires implanted in Cortex, Thalamus, Brainstem, Hypothalamus, Cerebellum, or other biological signals. Continuous voltage signals are scanned and filtered from neuron-recording microprobes. Candidate spike waveforms are captured and transferred to the host computer for sorting and storage. Real-time or off-line sorting results in datasets of accurate event times available for viewing from within the database or export to standard file formats. Slow voltage signal sources are recorded continuously.
Experiment Control: permitsaccurate detection of behavioral events from levers, nose pokes, touch screens, photodetectors, or other devices. Control is provided for AC or DC lights, solenoids, and retractable levers with fixed or random timing features via TTL output lines from the host computer. Multiple simultaneous experiments can be carried out. Control paradigms are easily created with the protocol language. Timing for control and recording via TTL are accurate to 1 millisecond.
Rate meter, histogram, raster, correlogram, events symbols, spreadsheet formats and database design allows flexible analysis via graphical outputs. Quantitative data organization allows output to MATLAB and standard statistical packages.
System Components: Biographics, Inc. hardware is designed to be state of the art, compact, inexpensive, and easy to support. The user can easily install the equipment and connect to a wide range of laboratory instruments and sensors.
Integrated Host Computer: The basic standard system is integrated into a single chassis with a 3.8 GHz P4 or AMD64 processor motherboard. Included are 2 GB of RAM, a 300 GB 7200 RPM ATA hard disk, and CD-R/W drive. A high performance graphics adapter allows display on one or two monitors. Video and sound cards allow streaming data input and output. Microsoft Windows, Ethernet and USB 2.0 are standard.
Instrumentation Module:Each Instrumentation Module provides up to 128 input amplifiers with cselectable digital filters and 24 -bit A/D conversion for data acquisition. Analog output is provided by an array of sixteen 16-bit D/A outputs. A 240 MHz Digital Signal Processor controls each group of sixteen input channels. Fast data transfer to the host is enabled by PCI bus interface. Larger systems are available. A separate preamplifier module provides power for 16 channel head stage plugs, for recording from electrode arrays.
External Interface Kit:Standard 48 channels of buffered TTL IO lines are included to connect to a wide variety of external devices, including photocells, solenoids and lights. An optional kit with PC board and power source allows 24 isolation modules for connection to experimental devices powered by DC or AC for control of single or multiple experiments.
Available Components: Micro wire arrays of varied configurations. Preamplifiers for EEG, EKG, EMG and spike waveform capture with individual band pass settings. Motorized commutators include 18 to 180 channels. An available Video frame timer/counter module synchronizes data events with video frames. One to eight channel photo emitter/detector arrays detect movement. A digital programmable motor controls treadmill speed and distance.
System Software: The MAGNET Software System is compatible with Microsoft Windows and includes data acquisition, real time experimental control, and data analysis utilizing standard, modern database designs.
Multi-channel Neuron Spike Sorter: Spike waveform segments of continuous voltage signals are captured, assigned a high resolution time stamp and transmitted to the host PC along with computer parameters for graphical display and for permanent storage. An on-line or off-line spike sorter feature allows each waveform to be coded as to whether a legal or illegal waveform has been captured according to multiple parameter sorting schemes.These can be saved, displayed, discarded after saving trial stamps, or discarded after resorting. Concurrent waveforms captured from the multiple wires can be sorted on-line or off-line. Continuous Capture Mode can be set to digitize and store an uninterrupted flow of data. This mode is used to store slow data from EMG, EKG, EEG, blood pressure, respiration, temperature, lever position, eye position or any parameter defined by a time varying voltage level.
Real-Time State Machine Control Program: Each system is provided with 48 or 96 bits of buffered digital I/O. Banks of 8 bits each are set for input or output under software control. Digital I/O events are timed accurately to within 1 millisecond. Output lines can source or sink 20 mA of current to drive peripheral devices such as optoisolators or relays. Video and audio output sequences can also be controlled. Hardware and software protocols allow accurate synchronization of data acquisition with external instrumentation. Users can easily design scripts to respond to external events, implement timers, control devices, etc.
Data Analysis: Data is organized in an indexed database to allow fast random access to timed event data across files and different experiments. Many graphical displays are standard. Data can be exported to other formats, including Stranger, NeuroExplorer and text.
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